Antispasmin DS

In various colic & post-surgical conditions, when the body is afflicted with pain or spasms, use Antispasmin DS to relax the muscles and provide safe & fast relief. Ask your doctor for the right dosage.

Drotaverine Hydrochloride promotes its antispasmolylic by inhibiting Phosphodiasterase, thereby incresing the availability of the cAMP in the smooth muscle cells. This results in increased activation of the Calcium pumps, reducing the availability of Ca++ and causing relaxation of smooth muscle. Increased availability of cAMP also activates the enzyme A-kinase to a greater extent, which again facilitates the smooth muscle relaxation mechanism. Thus Drotaverine alleviates spasm and pain.